Antiviral activity of CHO-SS cell-derived human omega interferon and other human interferons against HCV RNA replicons and related viruses.

@article{Buckwold2007AntiviralAO,
  title={Antiviral activity of CHO-SS cell-derived human omega interferon and other human interferons against HCV RNA replicons and related viruses.},
  author={Victor E. Buckwold and Jiayi Wei and Zhuhui Huang and Chunsheng Huang and Aysegul Nalca and Jay Wells and Julie D Russell and Barbara Collins and Roger G. Ptak and W. Christopher Lang and Curtis Scribner and Dennis Blanchett and Tom Alessi and Peter Langecker},
  journal={Antiviral research},
  year={2007},
  volume={73 2},
  pages={118-25}
}
The fully glycosylated human omega interferon produced from CHO-SS cells (glycosylated IFN-omega) has been shown to be well-tolerated in man and to induce a sustained virologic response in patients infected with hepatitis C virus (HCV). We examined the antiviral activity of glycosylated IFN-omega and various human IFNs (IFN-alpha, -beta, -gamma and non-glycosylated bacterial (Escherichia coli) recombinant IFN-omega (non-glycosylated IFN-omega)) against HCV RNA replicons and several viruses… CONTINUE READING