Antiviral activity and mode of action of extracts from neem seed kernel against duck plague virus in vitro1.

@article{Xu2012AntiviralAA,
  title={Antiviral activity and mode of action of extracts from neem seed kernel against duck plague virus in vitro1.},
  author={Jing Xu and Xinxiu Song and Zhi Qi Yin and Anchun Cheng and Renyong Jia and Youxing Deng and Keqiang Ye and Chao Shi and Chuanwei Lv and Wen-wen Zhang},
  journal={Poultry science},
  year={2012},
  volume={91 11},
  pages={2802-7}
}
Four fractions obtained from alcohol extracts of neem (Azadirachta indica) seed kernel by column chromatography were investigated for antivirus activity against the duck plague virus (DPV) in vitro. Duck embryo fibroblasts (DEF) infected with DPV were treated with the neem seed kernel extracts, and the effect of antivirus was judged by 3-(4,5)-dimethylthiahiazo (-z-y1)-3,5-di-phenytetrazoliumromide colorimetric method assay and direct immunofluorescence assay. The mode of action was tested by… CONTINUE READING