Antiviral Potency of Mushroom Constituents

  title={Antiviral Potency of Mushroom Constituents},
  author={Prabin Pradeep and Vidya Manju and Mohammad Feraz Ahsan},
  journal={Medicinal Mushrooms},
Mushrooms have various bioactive compounds, which have anticancer, antibacterial, antifungal, antiviral, antioxidant, and anti-inflammatory compounds. The limitation of natural antiviral compounds in the market and the viruses becoming resistant to currently available antivirals warranted the need for new antivirals with fewer side effects. Although many different compounds from various mushrooms (both edible and nonedible) have been isolated and shown to have antiviral effects, successful… 
Lectins purified from medicinal and edible mushrooms: Insights into their antiviral activity against pathogenic viruses.
The history, classification, purification techniques, structure-function relationship and different therapeutic applications of mushroom lectin are described, and antiviral activity, purifying and physicochemical characteristics of some mushroom lectins are focused on.
Current Antivirals and Novel Botanical Molecules Interfering With Herpes Simplex Virus Infection
Currently available anti-herpetic therapies, novel molecules being assessed in clinical trials and new botanical compounds reported in the last 20 years with antiviral activities against HSVs that might represent future treatments against these viruses are reviewed.
A Review on Remdesivir: An Alternative Antiviral Drug to Fight against COVID-19
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Survival of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Herpes Simplex Virus 1 (HSV-1) on Foods Stored at Refrigerated Temperature
The survival and high recovery of SARS-CoV-2 on certain foods highlight the importance of safe food handling practices in mitigating any public health concerns related to potentially contaminated foods.


Medicinal Mushrooms in Human Clinical Studies. Part I. Anticancer, Oncoimmunological, and Immunomodulatory Activities: A Review.
  • S. Wasser
  • Biology, Medicine
    International journal of medicinal mushrooms
  • 2017
High-quality, long-term, randomized, double-blind, placebo-controlled clinical studies of MMs, including well-sized population studies are definitely needed in order to yield statistical power showing their efficacy and safety, and clinical trials must obtain sufficient data on the efficacy andsafety of MM-derived drugs and preparations.
Mushroom Polysaccharides: Chemistry and Antiobesity, Antidiabetes, Anticancer, and Antibiotic Properties in Cells, Rodents, and Humans
The chemistry of mushroom polysaccharides and their reported antiobesity and antidiabetic properties as well as selected anticarcinogenic, antimicrobial, and antiviral effects that demonstrate their multiple health-promoting potential are surveyed.
The Pharmacological Potential of Mushrooms
This review describes pharmacologically active compounds from mushrooms with antimicrobial, antiviral, antitumor, antiallergic, immunomodulating, anti-inflammatory, antiatherogenic, hypoglycemic, hepatoprotective and central activities.
The anti-influenza virus effect of Phellinus igniarius extract
Virological assays revealed that the extract may interfere with one or more early events in the influenza virus replication cycle, including viral attachment to the target cell, which provides new insights into the use of P. igniarius as an anti-influenza medicine.
[Antiviral activity of aqueous extracts of the birch fungus Inonotus obliquus on the human immunodeficiency virus].
Fractions of aqueous and water-alcohol extracts of the birch fungus Inonotus obliquus have antiviral effect against the human immunodeficiency virus type 1 (HIV-1). Antiviral properties of low toxic
Fungus Cerrena unicolor as an effective source of new antiviral, immunomodulatory, and anticancer compounds.
It was indicated for the first time that the LAC and ex-LMS fractions exhibited anticancer activity from their cytotoxic or antiproliferative action against the investigated tumor cells at concentrations above 250 μg/ml and 10 μg/ ml, respectively.
Polysaccharide and extracts from Lentinula edodes: structural features and antiviral activity
It is concluded that aqueous and ethanol extracts and polysaccharide from Lentinula edodes act on the initial processes of the replication of both strains of virus.
Medicinal Mushroom Science: History, Current Status, Future Trends, and Unsolved Problems
The history, current status, and future trends in the study of medicinal mushrooms are analyzed to draw attention to many critically important unsolved problems in the future development of medicinal mushroom science in the 21st century.
Antiviral effects of two Ganoderma lucidum triterpenoids against enterovirus 71 infection.
GLTA and GLTB significantly inhibit the replication of the viral RNA of EV71 replication through blocking EV71 uncoating and may represent two potential therapeutic agents to control and treat EV71 infection.
Antiviral activity of carnosic acid against respiratory syncytial virus
It is demonstrated that carnosic acid, a natural compound that has already been shown to be safe for human consumption, has anti-viral activity against hRSV, efficiently blocking the replication of this virus.