Antiviral NK cell responses in HIV infection: I. NK cell receptor genes as determinants of HIV resistance and progression to AIDS

@article{Iannello2008AntiviralNC,
  title={Antiviral NK cell responses in HIV infection: I. NK cell receptor genes as determinants of HIV resistance and progression to AIDS},
  author={Alexandre Iannello and Olfa D{\'e}bbeche and Suzanne Samarani and Ali Ahmad},
  journal={Journal of Leukocyte Biology},
  year={2008},
  volume={84}
}
NK cells play an important role in controlling viral infections. They can kill virus‐infected cells directly as well as indirectly via antibody‐dependent, cell‐mediated cytotoxicity. They need no prior sensitization and expansion for this killing. NK cells are also considered as important regulators of antiviral immune responses. They do so by secreting a multitude of soluble mediators and by directly interacting with other immune cells, e.g., dendritic cells. NK cells do not possess a single… 
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