Antiviral Goes Viral: Harnessing CRISPR/Cas9 to Combat Viruses in Humans.

@article{Soppe2017AntiviralGV,
  title={Antiviral Goes Viral: Harnessing CRISPR/Cas9 to Combat Viruses in Humans.},
  author={Jasper Adriaan Soppe and Robert Jan Lebbink},
  journal={Trends in microbiology},
  year={2017},
  volume={25 10},
  pages={
          833-850
        }
}
The clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) systems are RNA-guided sequence-specific prokaryotic antiviral immune systems. In prokaryotes, small RNA molecules guide Cas effector endonucleases to invading foreign genetic elements in a sequence-dependent manner, resulting in DNA cleavage by the endonuclease upon target binding. A rewired CRISPR/Cas9 system can be used for targeted and precise genome editing in eukaryotic cells. CRISPR/Cas has… CONTINUE READING
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