Comparison of remdesivir and favipiravir - the anti-Covid-19 agents mimicking purine RNA constituents.
- Medicine, BiologyBiomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia
Favipiravir has shown various benefits when administered in mild and moderate cases of COVID-19, while remdesivir was more beneficial in more severe cases of the disease, and the evidence in favor of favipirs is compromised by the small number and low-quality of trials conducted.
Combating the Coronavirus Pandemic: Early Detection, Medical Treatment, and a Concerted Effort by the Global Community
- Medicine, BiologyResearch
Advances and challenges in the rapid detection of COVID-19 by targeting nucleic acids, antigens, or antibodies are reviewed and potential treatments and vaccines against CO VID-19 are summarized.
Prescribed drugs containing nitrogen heterocycles: an overview
- ChemistryRSC advances
Heteroatoms as well as heterocyclic scaffolds are frequently present as the common cores in a plethora of active pharmaceuticals natural products. Statistically, more than 85% of all biologically…
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Emerging antiviral drugs.
- Biology, MedicineExpert opinion on emerging drugs
Among the newly described antiviral agents that may be developed into drugs are, for the treatment of human papilloma virus (HPV) infections, cPrPMEDAP and cyclosporin A derivatives such as the non-immunosuppressive Debio-025.
Antiviral strategies against influenza virus: towards new therapeutic approaches
- BiologyCellular and Molecular Life Sciences
An overview of novel strategies targeting the virus and/or the host cell for counteracting influenza virus infection and several new classes of antiviral agents targeting viral replication mechanisms or cellular proteins/processes are under development.
Recent highlights in the development of new antiviral drugs.
- Medicine, Biology
Recent highlights in the development of new antiviral drugs
- Medicine, BiologyCurrent Opinion in Microbiology
Antiviral drugs in current clinical use.
- Medicine, BiologyJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology
The current armamentarium for the chemotherapy of viral infections consists of 37 licensed antiviral drugs and the combination of ribavirin with (pegylated) interferon-alpha has received increased acceptance for the treatment of hepatitis C virus (HCV) infections.
Targeting the host or the virus: Current and novel concepts for antiviral approaches against influenza virus infection
- BiologyAntiviral Research
Antiviral agents active against influenza A viruses
- BiologyNature reviews. Drug discovery
Key PointsSeveral drugs are available that could be used, either alone or in combination, for the treatment (prophylaxis or therapy) of an influenza pandemic. These include adamantan(amin)e…