Antiviral Action of Methylated β-Lactoglobulin on the Human Influenza Virus A Subtype H3N2.

@article{Sitohy2010AntiviralAO,
  title={Antiviral Action of Methylated β-Lactoglobulin on the Human Influenza Virus A Subtype H3N2.},
  author={Mahmoud Z. Sitohy and Bernard Besse and Sylviane Billaudel and Thomas Haertl{\'e} and J. M. Chobert},
  journal={Probiotics and antimicrobial proteins},
  year={2010},
  volume={2 2},
  pages={104-11}
}
Antiviral activity of methylated β-lactoglobulin (Met-BLG) against H3N2 infected into MDCK cell lines depended on concentration of Met-BLG, viral load, and duration of infection. IC50% of the hemagglutination activity for 1 and 0.2 MOI (multiplicity of infection) after 24 h of incubation at 37 °C in the presence of 5% CO2 were 20 ± 0.8 and 17 ± 0.7 μg mL(-1) Met-BLG, respectively. Longer incubation period (4 days) was associated with low IC50% of the hemagglutination activity (7.1 ± 0.3 μg mL… CONTINUE READING
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