Antivascular effects of pulsed low intensity ultrasound and microbubbles in mouse tumors

@article{Goertz2008AntivascularEO,
  title={Antivascular effects of pulsed low intensity ultrasound and microbubbles in mouse tumors},
  author={D. E. Goertz and Raffi Karshafian and Kullervo Hynynen},
  journal={2008 IEEE Ultrasonics Symposium},
  year={2008},
  pages={670-673}
}
In this study we investigate the feasibility of inducing transient and sustained blood flow changes in murine tumors with pulsed low intensity ultrasound. Subcutaneous xenograft melanoma tumors were situated in the hind limbs of mice and exposed to 1 MHz (740 kPa) pulsed ultrasound following a bolus injection of Definitytrade microbubbles. Flow within the… CONTINUE READING