Antitussive and central respiratory depressant effects of Stemona tuberosa.

@article{Xu2010AntitussiveAC,
  title={Antitussive and central respiratory depressant effects of Stemona tuberosa.},
  author={Yan-tong Xu and Pang-Chui Shaw and Ren‐Wang Jiang and Po Ming Hon and Yiu-Man Chan and Paul Pui-Hay But},
  journal={Journal of ethnopharmacology},
  year={2010},
  volume={128 3},
  pages={
          679-84
        }
}
Studies on antitussive effect of Tectona grandis roots using a cough model induced by sulfur dioxide gas in guinea pigs.
Objectives : Anti-tussive drugs are among the most widely used medications world wide; however no new class of drugs has been introduced into the market by keeping this point in mind. This attempt is
Antitussive Activity of Pseudostellaria heterophylla (Miq.) Pax Extracts and Improvement in Lung Function via Adjustment of Multi-Cytokine Levels
TLDR
The results suggest that ethyl acetate fraction has antitussive activity related to its improvement in lung function via attenuation of airway inflammation by adjustment of multi-cytokine levels.
Therapeutic Potential of Alkaloids in Cough Treatment
TLDR
Cough is an important characteristics of larynx and respiratory system which help out in the removal of foreign substances and secretions and prevent aspiration of food and fluids and thus prevent choking (suffocation) which may provoked by the presence of such agents.
Alkaloids from the Roots and Leaves of Stichoneuron halabalensis and their Acetylcholinesterase Inhibitory Activities
A study of the hitherto unreported Stichoneuron halabalensis Inthachub led to the characterization of the known compounds (+)-α-tocopherol and (R)-(+)-goniothalamin; four known Stemona alkaloids,
Structural classification and biological activities of Stemona alkaloids
  • H. Greger
  • Chemistry
    Phytochemistry Reviews
  • 2019
Stemona alkaloids represent a unique class of natural products exclusively known from the three genera Stemona, Stichoneuron, and Croomia of the monocotyledonous family Stemonaceae. Structurally they
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References

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Antitussive activity of Stemona alkaloids from Stemona tuberosa.
TLDR
It is demonstrated, for the first time, that compounds 1 and 5 showed significant antitussive activities in guinea pig after cough induction by citric acid aerosol stimulation.
Antitussive effects of Stemona tuberosa with different chemical profiles.
Oral absorption and antitussive activity of tuberostemonine alkaloids from the roots of Stemona tuberosa.
TLDR
All three alkaloids exhibited dose-dependent inhibitory effects on citric acid-induced cough in guinea pigs after intraperitoneal administration and demonstrated a moderate permeability in Caco-2 monolayer cells, indicating that all four alkaloid tested had reasonable oral absorption.
Antitussive stemoninine alkaloids from the roots of Stemona tuberosa.
TLDR
Investigation of the roots of Stemona tuberosa afforded five minor constituents, stemoenonine, which were elucidated by 1D and 2D NMR spectra and other spectroscopic studies and exhibited strong antitussive activity after oral and intraperitoneal administrations.
The stemona alkaloids.
Structural relationships, distribution and biological activities of stemona alkaloids.
TLDR
Stemona alkaloids represent a unique class of natural products exclusively isolated from the monocotyledonous family Stemonaceae comprising three genera mainly distributed in southeast Asia and showing species-specific accumulation trends towards certain structural types represent valuable chemosystematic criteria.
Current and future centrally acting antitussives
  • D. Bolser
  • Medicine
    Respiratory Physiology & Neurobiology
  • 2006
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