Corpus ID: 74323985

Antitussive Effect of Thymoquinone, a Constituent of Nigella Sativa Seeds, in Guinea Pigs

@inproceedings{Hosseinzadeh2008AntitussiveEO,
  title={Antitussive Effect of Thymoquinone, a Constituent of Nigella Sativa Seeds, in Guinea Pigs},
  author={H. Hosseinzadeh and M. Eskandari and T. Ziaee},
  year={2008}
}
  • H. Hosseinzadeh, M. Eskandari, T. Ziaee
  • Published 2008
  • Medicine
  • The antitussive activity of thymoquinone, a constituent of Nigella sativa seeds, was evaluated using the nebulized solution of citric acid 20 % in guinea pigs. Thymoquinone and codeine were injected intraperitoneally. Thymoquinone (20 and 40 mg/kg) and codeine (5 mg/kg), a prototype antitussive agent, reduced the number of cough in animals. The antitussive effect of these agents was antagonized by pretreatment with naloxone (2 mg/kg), an opioid receptor antagonist. These results suggest that… CONTINUE READING
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