Antitussive, expectorant, and anti-inflammatory activities of four caffeoylquinic acids isolated from Tussilago farfara

  title={Antitussive, expectorant, and anti-inflammatory activities of four caffeoylquinic acids isolated from Tussilago farfara},
  author={Qi-Zhen Wu and Dong‐Xia Zhao and Juan Xiang and Mian Zhang and Chaofeng Zhang and Xiang-hong Xu},
  journal={Pharmaceutical Biology},
  pages={1117 - 1124}
Abstract Context: The flower bud of Tussilago farfara L. (Compositae) (FTF) is one of the traditional Chinese medicinal herbs used to treat cough, phlegm, bronchitic, and asthmatic conditions. Objective: The objective of this study is to isolate four caffeoylquinic acids from the ethyl acetate extract (EtE) of FTF and to evaluate their antitussive, expectorant, and anti-inflammatory activities. Materials and methods: The structures of compounds 1–4 isolated from EtE were determined by spectral… 

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[Studies on chemical constituents in the buds of Tussilago farfara].

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    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  • 2007
Compounds 2-5 were isolated from the genus Tussilago farfara for the first time and structurally elucidated by NMR and MS evidences.

Cough, asthma, and cysteinyl-leukotrienes.

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