Antitumour quinones.

  title={Antitumour quinones.},
  author={Christian Asche},
  journal={Mini reviews in medicinal chemistry},
  volume={5 5},
Quinones still comprise one of the largest classes of antitumour agents. For example, the anthracycline antibiotics are among the most utilised anticancer agents ever developed. Many other quinones were tested for their anticancer activity. Though there are general and well-established mechanisms for quinone toxicity, the exact contribution of the quinone moiety to the cytotoxic effect remains frequently uncertain. However, DNA represents the main target for quinoid antitumour agents and most… CONTINUE READING
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