Antitumoral effects of Melissa officinalis on breast cancer in vitro and in vivo.

@article{Saraydin2012AntitumoralEO,
  title={Antitumoral effects of Melissa officinalis on breast cancer in vitro and in vivo.},
  author={Serpil Unver Saraydin and Ersin Tuncer and Bektaş Tepe and Şule Karadayi and Hatice {\"O}zer and M. Berke Sen and Kursat Karadayi and Deniz Inan and Şahande Elag{\"o}z and Z{\"u}beyde Akın Polat and Mustafa Duman and Mustafa Turan},
  journal={Asian Pacific journal of cancer prevention : APJCP},
  year={2012},
  volume={13 6},
  pages={2765-70}
}
BACKGROUND There is a long standing interest in the identification of medicinal plants and derived natural products for developing cancer therapeutics. Here we investigated the antiproliferative properties of Melissa officinalis (MO) from Turkey on breast cancer. METHODS MO extracts were studied for cytotoxicity against breast cancer cell lines (MCF-7, MDA-MB-468 and MDA-MB-231). In vitro apoptosis studies were performed by annexin V staining and flow cytometry analyses. Immunohistochemistry… CONTINUE READING