Antitumoral activity of rapamycin in renal angiomyolipoma associated with tuberous sclerosis complex.

@article{Wienecke2006AntitumoralAO,
  title={Antitumoral activity of rapamycin in renal angiomyolipoma associated with tuberous sclerosis complex.},
  author={Ralf Wienecke and Ingrid Fackler and Ulrich Linsenmaier and Karin Mayer and Thomas Licht and Matthias Kretzler},
  journal={American journal of kidney diseases : the official journal of the National Kidney Foundation},
  year={2006},
  volume={48 3},
  pages={e27-9}
}
A 19-year old patient with tuberous sclerosis presented with a renal angiomyolipoma. Because animal trials of tuberous sclerosis showed an effect of rapamycin on renal tumors, our patient was administered rapamycin for 6 months. During this time, the renal angiomyolipoma shrank significantly, regrew during an 8-month period, and decreased in size again after readministration of rapamycin. 

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