Antitumoral activity of a xanthate compound. I. Cytotoxicity studies with neoplastic cell lines in vitro.

@article{Schick1989AntitumoralAO,
  title={Antitumoral activity of a xanthate compound. I. Cytotoxicity studies with neoplastic cell lines in vitro.},
  author={Hans D. Schick and Eberhard Amtmann and Wolfgang E Berdel and Susanne Danhauser-Riedl and Anneliese Reichert and Gabriela Steinhauser and Johann Rastetter and Gabriele Sauer},
  journal={Cancer letters},
  year={1989},
  volume={46 2},
  pages={
          143-7
        }
}
Xanthate derivatives were shown previously to display antitumor activity against transformed fibroblasts and lymphoma cells in combination with monocarboxylic acids [1]. Various malignant cell lines of human origin were treated in vitro to explore the range of antitumoral activity of the compounds. The combination of tricyclodecan-9-yl-xanthogenate (D 609) with undecanoic acid (C11) exerted dose dependent cytotoxic and antiproliferative effects on cell lines both from solid tumors… CONTINUE READING
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