Antitumor response of CD14+/CD16+ monocyte subpopulation.

  title={Antitumor response of CD14+/CD16+ monocyte subpopulation.},
  author={Anna Szaflarska and Monika Baj-Krzyworzeka and Maciej Siedlar and Kazimierz Węglarczyk and Irena Ruggiero and Barbara Hajto and Marek Zembala},
  journal={Experimental hematology},
  volume={32 8},
OBJECTIVE Two main subpopulations of human blood monocytes are distinguished on the basis of CD14 and CD16 expression: the major population with enhanced expression of CD14 (CD14++ monocytes) and the minor one with a weak expression of CD14 coexpressing CD16 (CD14+/CD16+ monocytes). As monocytes and macrophages are involved in antitumor response of the host, we assessed the ability of CD14+/CD16+ monocytes to produce cytokines (intracellular expression, release) and reactive oxygen and nitrogen… CONTINUE READING