Antitumor protection using murine dendritic cells pulsed with acid-eluted peptides from in vivo grown tumors of different immunogenicities.

@article{Ribas1999AntitumorPU,
  title={Antitumor protection using murine dendritic cells pulsed with acid-eluted peptides from in vivo grown tumors of different immunogenicities.},
  author={Antoni Ribas and Lynne A. Bui and Lisa H Butterfield and Charles Mahlon Jr. Vollmer and Syed Jilani and Vivian Beck Dissette and John A. Glaspy and William John Hannan McBride and James Steven Economou},
  journal={Anticancer research},
  year={1999},
  volume={19 2A},
  pages={
          1165-70
        }
}
Peptides extracted from tumor cells after mild acid treatment can function as antigenic epitopes when presented by cultured dendritic cells. Peptides were extracted from four tumors syngeneic to C3H mice, three weakly immunogenic tumors (FSA, MCAK, HCA) and one non-immunogenic tumor (NFSA). Dendritic cells pulsed with peptides extracted from the three weakly immunogenic tumors partially protect mice from a tumor challenge with the parental cell line. This protection was evident by a slower rate… CONTINUE READING

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 14 CITATIONS