Antitumor effect and tumor level of 5‐fluoro‐2‐deoxyuridylate following oral administration of tetradecyl 2'‐deoxy‐5‐fluoro‐5'‐uridylate

@article{Nakajima1992AntitumorEA,
  title={Antitumor effect and tumor level of 5‐fluoro‐2‐deoxyuridylate following oral administration of tetradecyl 2'‐deoxy‐5‐fluoro‐5'‐uridylate},
  author={Y. Nakajima and M. Ligo and A. Hoshi},
  journal={Anti-Cancer Drugs},
  year={1992},
  volume={3},
  pages={289–292}
}
  • Y. Nakajima, M. Ligo, A. Hoshi
  • Published 1992
  • Medicine
  • Anti-Cancer Drugs
  • The antltumor effect and tumor levels of 5-fluoro-2'-deoxyuridylate (FdUMP) following oral administration of tetradecyl 2'-deoxy-5-fluoro-5'-urldylate (TT-62) were compared with those attained following intravenous (i.v.) or intraperitoneal (i.p.) administration of 5-fluorouracil (5-FU) or 5-fluoro-2'-deoxyuridine (FUdR) in BDF1 mice bearing murine mammary adenocarcinoma 755 and athymic mice bearing the transplantable human colon adenocarcinoma LS174T. Oral administration of TT-62 showed a… CONTINUE READING
    1 Citations
    Fluorine-Containing Diazines in Medicinal Chemistry and Agrochemistry
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