Antitumor and immunomodulating activities of endo-biopolymers obtained from a submerged culture of Pleurotus eryngii

  title={Antitumor and immunomodulating activities of endo-biopolymers obtained from a submerged culture of Pleurotus eryngii},
  author={Yong-Tae Jeong and Sang-Chul Jeong and Young-Ah Gu and Rezuanul Islam and Chi-Hyun Song},
  journal={Food Science and Biotechnology},
  • Yong-Tae Jeong, Sang-Chul Jeong, +2 authors Chi-Hyun Song
  • Published 2010
  • Chemistry
  • Food Science and Biotechnology
  • Antitumor effect of endo-biopolymer (EBP) obtained from submerged mycelial culture of Pleurotus eryngii was investigated by using Sarcoma-180 bearing mice. The administration of EBP, intraperitoneally (10 to 80 mg/kg BW) at all dose ranges, inhibited the growth of the solid tumor and simultaneously increased the activity of natural killer (NK) cells significantly. While, 40 mg/kg BW treated group reduced the tumor formation (53.1%), and increased the NK cell activity of splenocytes (25.0%) to a… CONTINUE READING
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