Antitumor activity of palmitic acid found as a selective cytotoxic substance in a marine red alga.

@article{Harada2002AntitumorAO,
  title={Antitumor activity of palmitic acid found as a selective cytotoxic substance in a marine red alga.},
  author={Hideki Harada and Uki Yamashita and Hideyuki Kurihara and Eri Fukushi and Jun Kawabata and Yuto Kamei},
  journal={Anticancer research},
  year={2002},
  volume={22 5},
  pages={2587-90}
}
In a previous report, we discussed an extract from a marine red alga, Amphiroa zonata, which shows selective cytotoxic activity to human leukemic cells, but no cytotoxicity to normal human dermal fibroblast (HDF) cells in vitro. In this study, we identified palmitic acid, a selective cytotoxic substance from the marine algal extract, and investigated its biological activities. At concentrations ranging from 12.5 to 50 micrograms/ml, palmitic acid shows selective cytotoxicity to human leukemic… CONTINUE READING

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