Antitumor activity of methanolic extract of Cassia fistula L. seed against Ehrlich ascites carcinoma.

@article{Gupta2000AntitumorAO,
  title={Antitumor activity of methanolic extract of Cassia fistula L. seed against Ehrlich ascites carcinoma.},
  author={M. Ravindranath Gupta and Upal Kanti Mazumder and Nibedita Rath and Dilip K. Mukhopadhyay},
  journal={Journal of ethnopharmacology},
  year={2000},
  volume={72 1-2},
  pages={
          151-6
        }
}
Effects of methanolic extract (ME) of Cassia fistula seed on the growth of Ehrlich ascites carcinoma (EAC) and on the life span of tumor bearing mice were studied. ME treatment showed an increase of life span, and a decrease in the tumor volume and viable tumor cell count in the EAC tumor hosts. Cytological studies have revealed a reduction in the mitotic activity, and the appearance of membrane blebbing and intracytoplasmic vacuoles in the treated tumor cells. Improvement in the hematological… CONTINUE READING

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