Corpus ID: 34274461

Antitumor activity of homo-aza-steroidal esters of p-N, N-bis(2-chloroethyl)aminophenoxyacetic acid.

@article{Catsoulacos1993AntitumorAO,
  title={Antitumor activity of homo-aza-steroidal esters of p-N, N-bis(2-chloroethyl)aminophenoxyacetic acid.},
  author={P. Catsoulacos and D. Catsoulacos},
  journal={Anticancer research},
  year={1993},
  volume={13 4},
  pages={
          1203-8
        }
}
  • P. Catsoulacos, D. Catsoulacos
  • Published 1993
  • Chemistry, Medicine
  • Anticancer research
  • The homo-aza-steroidal esters of carboxylic derivatives of N, N-bis (2-chloroethyl) aniline are reviewed. In particular, we discuss the antitumor activity of the esters of homo-aza steroids in which the p-N,N-bis(2-chloroethyl)aminophenoxyacetic acid is linked to the C-3 or C-17 position, while the lactam nucleus is linked to the D or A ring of the modified steroid respectively. The current literature indicates clearly that the potential of these esters is due to the synergistic activity of… CONTINUE READING
    24 Citations

    Topics from this paper

    Synthesis and cytotoxicity of 17a-aza-D-homo-androster-17-one derivatives.
    • 22
    Synthesis and Evaluation of Some New Aza-B-homocholestane Derivatives as Anticancer Agents
    • 10
    • PDF