Antitumor activity of gallium and lanthanum: role of cation-cell membrane interaction.


Using the vital dye inclusion method and the radioisotopic study of Ca2+-transport, we have investigated the involvement of the gallium and lanthanum plasma-membrane interaction in the cytotoxic and antitumor characteristics of both cations. The experimental results support the hypothesis that such an interaction is the principal cause of antitumor activity… (More)


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