Antitumor activity of balsam fir oil: production of reactive oxygen species induced by alpha-humulene as possible mechanism of action.

@article{Legault2003AntitumorAO,
  title={Antitumor activity of balsam fir oil: production of reactive oxygen species induced by alpha-humulene as possible mechanism of action.},
  author={Jean Legault and Wivecke Dahl and Eric D{\'e}biton and Andr{\'e} Pichette and Jean-Claude Madelmont},
  journal={Planta medica},
  year={2003},
  volume={69 5},
  pages={402-7}
}
The antitumor activity of the essential oil of Abies balsamea (balsam fir oil) was evaluated against several solid tumor cell lines including MCF-7, PC-3, A-549, DLD-1, M4BEU and CT-26. Balsam fir oil was found to be active against all the solid tumor cell lines tested, with GI 50 values ranging between 0.76 and 1.7 mg/mL. The oil was analyzed by GC-MS and… CONTINUE READING