• Corpus ID: 7421460

Antitumor activity of Bulgarian herb Tribulus terrestris L. on human breast cancer cells

@inproceedings{Angelova2013AntitumorAO,
  title={Antitumor activity of Bulgarian herb Tribulus terrestris L. on human breast cancer cells},
  author={Svetla Angelova and Zlatina Gospodinova and Maria Emileva Krasteva and Georgi Antov and Valentin S. Lozanov and Tsanko L. Markov and Stefan Bozhanov and Elena Ivanova Georgieva and Vanio Ivanov Mitev},
  year={2013}
}
Medicinal plants have been intensively studied as a source of antitumor compounds. Due to the beneficial climate conditions Bulgarian herbs have high pharmacological potential. Currently, the antitumor effect of the Bulgarian medicinal plant Tribulus terrestris L. on human cancer cell lines is not studied. The main active compounds of the plant are the steroid saponins. The present study aims to analyze the effect on cell viability and apoptotic activity of total extract and saponin fraction of… 

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References

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TLDR
TT is less toxic for normal human skin fibroblasts in comparison to many cancer lines investigated in previous studies, and the molecular mechanism of this cytotoxicity involves up- and downregulation of polyamines’ homeostasis, suppression of proliferation, and induction of apoptosis.
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TLDR
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TLDR
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TLDR
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