Antitumor activity of (-)-alpha-bisabolol-based thiosemicarbazones against human tumor cell lines.

@article{DaSilva2010AntitumorAO,
  title={Antitumor activity of (-)-alpha-bisabolol-based thiosemicarbazones against human tumor cell lines.},
  author={Alan Patricio Da Silva and Manuele V. Martini and Cec{\'i}lia M A de Oliveira and S{\'i}lvio Cunha and Jo{\~a}o Ernesto de Carvalho and Ana L{\'u}cia Tasca Gois Ruiz and Cleuza Conceiç{\~a}o da Silva},
  journal={European journal of medicinal chemistry},
  year={2010},
  volume={45 7},
  pages={
          2987-93
        }
}
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47 Citations

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Overall, the interaction HSA:MTSC could provide therapeutic benefits, improving its cytotoxic efficacy and tolerability.
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TLDR
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TLDR
Compound exhibited the most potent activity against HGC-27 as compared with the reference compound, sindaxel, and could be used as a lead compound to search new chiral thiosemicarbazone derivatives as antiproliferative agents.
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Antitrypanosomal Activity of Novel Benzaldehyde-Thiosemicarbazone Derivatives from Kaurenoic Acid †
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The results show that the structural modifications accomplished enhanced the antitrypanosomal activity of these compounds.
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