Antituberculous Immunity Induced in Mice by Vaccination with Killed Tubercle Bacilli or with a Soluble Bacillary Extract

@article{Weiss1955AntituberculousII,
  title={Antituberculous Immunity Induced in Mice by Vaccination with Killed Tubercle Bacilli or with a Soluble Bacillary Extract},
  author={David Walter Weiss and Ren{\'e} J. Dubos},
  journal={The Journal of Experimental Medicine},
  year={1955},
  volume={101},
  pages={313 - 330}
}
It proved possible to increase the resistance of mice to tuberculous infection by vaccinating them with a suspension of avirulent tubercle bacilli killed by exposure to 2 per cent phenol. This increase in resistance was demonstrated by two different techniques: (a) observation of survival time of vaccinated animals following challenge infection with a large dose of virulent bacilli, and (b) determination of numbers of virulent bacilli in the spleens of animals 2 weeks after injection of a small… CONTINUE READING
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Les Lipoides dam les bacilles tuberculeux et la tuberculose

  • L. Ngre
  • 1950

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