Antitubercular inhaled therapy: opportunities, progress and challenges.

  title={Antitubercular inhaled therapy: opportunities, progress and challenges.},
  author={Rajesh Kumar Pandey and Gopal Krishan Khuller},
  journal={The Journal of antimicrobial chemotherapy},
  volume={55 4},
Pulmonary tuberculosis remains the commonest form of this disease and the development of methods for delivering antitubercular drugs directly to the lungs via the respiratory route is a rational therapeutic goal. The obvious advantages of inhaled therapy include direct drug delivery to the diseased organ, targeting to alveolar macrophages harbouring the mycobacteria, reduced risk of systemic toxicity and improved patient compliance. Research efforts have demonstrated the feasibility of various… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 62 extracted citations

Natural carriers for application in tuberculosis treatment.

Journal of microencapsulation • 2013
View 4 Excerpts
Highly Influenced

Inhalable microparticles containing large payload of anti-tuberculosis drugs.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences • 2007
View 4 Excerpts
Highly Influenced

Alpha ketoglutarate nanoparticles: A potentially effective treatment for cyanide poisoning.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V • 2018
View 2 Excerpts


Publications referenced by this paper.
Showing 1-10 of 48 references

Adjunctive salvage therapy with inhaled aminoglycosides for patients with persistent smear-positive pulmonary tuberculosis.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America • 2001
View 2 Excerpts
Highly Influenced

Endobronchial tuberculosis.

Expert review of anti-infective therapy • 2004
View 1 Excerpt

Similar Papers

Loading similar papers…