Antitubercular constituents of Valeriana laxiflora.

  title={Antitubercular constituents of Valeriana laxiflora.},
  author={J Q Gu and Yuehong Wang and Scott G Franzblau and Gloria Montenegro and Danzhou Yang and Barbara N. Timmermann},
  journal={Planta medica},
  volume={70 6},
Antitubercular bioassay-guided fractionation of the n-hexane- and CH (2)Cl (2)-soluble extracts of the above-ground biomass and roots of Valeriana laxiflora led to the isolation of a new iridolactone, (4R,5R,7S,8S,9S)-7-hydroxy-8-hydroxymethyl-4-methyl-perhydrocyclopenta[ c]pyran-1-one ( 1), and a new lignan, (+)-1-hydroxy-2,6-bis- epi-pinoresinol ( 2), along with eleven known compounds, betulin ( 3), betulinic acid ( 4), 5,7-dihydroxy-3,6,4'-trimethoxyflavone ( 5), 23-hydroxyursolic acid ( 6… CONTINUE READING
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