• DOI:10.1055/S-2005-837786
Corpus ID: 43200201

Antitubercular constituents from the roots of Engelhardia roxburghiana.

@article{Lin2005AntitubercularCF,
  title={Antitubercular constituents from the roots of Engelhardia roxburghiana.},
  author={Wen-Yu Lin and C. Peng and I. Tsai and Jih-Jung Chen and M. Cheng and I. Chen},
  journal={Planta medica},
  year={2005},
  volume={71 2},
  pages={
          171-5
        }
}

• Wen-Yu Lin, C. Peng, +3 authors I. Chen
• Published 2005
• Chemistry, Medicine
• Planta medica

Three new compounds, engelhardione, (-)-5-hydroxy-4-methoxy-1-tetralone, and 3-methoxycarbonyl-1,5-dihydroxyanthraquinone, together with twelve known compounds have been isolated from the roots of Engelhardia roxburghiana. The structures of these new compounds were determined through spectral analyses. Engelhardione, 3-methoxyjuglone, and (-)-4-hydroxy-1-tetralone showed antitubercular activities with MIC values=3.125, 3.125, and 6.25 microg/mL against Mycobacterium tuberculosis 90-221,387… Expand

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