Antitubercular and cytotoxic tigliane-type diterpenoids from Croton tiglium.

Abstract

Five new tigliane diterpene esters (1-5), highly oxygenated tetracyclic diterpenoid carbon skeleton, together with three known analogues (6-8) were isolated from the leaves of Croton tiglium. Extensive NMR and mass spectroscopic analysis were used to elucidate their structures. Most of the isolated compounds were tested for their cytotoxic and… (More)
DOI: 10.1016/j.bmcl.2016.09.002

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