Antitubercular Diazine Carboxamides.

@article{Rogers1952AntitubercularDC,
  title={Antitubercular Diazine Carboxamides.},
  author={E. F. Rogers and William J. Leanza and H. J. Becker and Alexander R Matzuk and R. C. O'neill and Arthur J. Basso and Gustav A Stein and Morris Solotorovsky and Francis J. Gregory and Karl Pfister},
  journal={Science},
  year={1952},
  volume={116 3010},
  pages={
          253-4
        }
}
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Pyrazinoic Acid Amide-An Agent Active Against Experimental Murine Tuberculosis
Conclusions 1. These data contribute to the importance of niacinamide derivatives as a new class of antituberculosis agents. One of these, pyrazinoic acid amide, is active when administered by
Studies on biological oxidations; the metabolism of lung as determined by a study of slices and ground tissue.
TLDR
Studies on the metabolism of the lung, as performed in slices and in ground tissue, are presented and show not only destruction of some biochemical activities but also appearance of others normally inhibited in the intact cell.
The effect of nicotinic acid amide on experimental tuberculosis of white mice.
Abstract The oral administration of 0.5 to 0.75 per cent of nicotinic acid amide in the diet will markedly suppress the spread of tuberculosis in experimentally infected mice. This amount of