Antitrypanosomal compounds from the essential oil and extracts of Keetia leucantha leaves with inhibitor activity on Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase.

@article{Bero2013AntitrypanosomalCF,
  title={Antitrypanosomal compounds from the essential oil and extracts of Keetia leucantha leaves with inhibitor activity on Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase.},
  author={Joanne Bero and Claire Beaufay and V{\'e}ronique Hannaert and Marie-France H{\'e}rent and Pam. Michels and Jo{\"e}lle Quetin-Leclercq},
  journal={Phytomedicine : international journal of phytotherapy and phytopharmacology},
  year={2013},
  volume={20 3-4},
  pages={
          270-4
        }
}
Keetia leucantha is a West African tree used in traditional medicine to treat several diseases among which parasitic infections. The dichloromethane extract of leaves was previously shown to possess growth-inhibitory activities on Plasmodium falciparum, Trypanosoma brucei brucei and Leishmania mexicana mexicana with low or no cytotoxicity (>100 μg/ml on human normal fibroblasts) (Bero et al. 2009, 2011). In continuation of our investigations on the antitrypanosomal compounds from this… Expand
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