Antithrombotic Effect of Kaempferia galanga L. and Curcuma xanthorrhiza Roxb. on Collagen-epinephrine Induced Thromboembolism In Mice

  title={Antithrombotic Effect of Kaempferia galanga L. and Curcuma xanthorrhiza Roxb. on Collagen-epinephrine Induced Thromboembolism In Mice},
  author={Fadlina Chany Saputri and Chavella Avatara},
  journal={Pharmacognosy Journal},
Objective: Kaempferia galanga L. and Curcuma xanthorrhiza Roxb. have been proven to possess antiplatelet activity in vitro. The aim of this study is to investigate the antithrombotic effect of the rhizome extracts of Kaempferia galanga L. and Curcuma xanthorrhiza Roxb in a mouse thrombotic model. Methods: The ethanol extracts of K. galanga and C. xanthorrhiza were orally administered with three different doses (7, 14 and 28 mg/20 g BW) in two experimental mouse models. Bleeding time… Expand
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