Antithrombin upregulates AMP-activated protein kinase signalling during myocardial ischaemia / reperfusion injury

@inproceedings{Ma2018AntithrombinUA,
  title={Antithrombin upregulates AMP-activated protein kinase signalling during myocardial ischaemia / reperfusion injury},
  author={Yina Ma and Jinli Wang and Junjie Gao and Hui Yang and Yanqing Wang and Chandrashekhara Manithody and Ji Li and Alireza R Rezaie},
  year={2018}
}
Antithrombin (AT) is a protein of the serpin superfamily involved in regulation of the proteolytic activity of the serine proteases of the coagulation system. AT is known to exhibit anti-inflammatory and cardioprotective properties when it binds to heparan sulfate proteo glycans (HSPGs) on vascular cells. AMP-activated protein kinase (AMPK) plays an important cardioprotective role during myocardial ischaemia and reperfusion (I/R). To determine whether the cardioprotective signaling function of… CONTINUE READING

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