Antithrombin reduces shedding of the endothelial glycocalyx following ischaemia/reperfusion.

Abstract

AIMS Antithrombin is an important inhibitor of the coagulation system, additionally exerting specific anti-inflammatory effects on endothelial cells. Healthy vascular endothelium is coated by the endothelial glycocalyx, diminution of which increases capillary permeability, e.g. after ischaemia. Antithrombin is known to infiltrate the glycocalyx, binding to… (More)
DOI: 10.1093/cvr/cvp097

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@article{Chappell2009AntithrombinRS, title={Antithrombin reduces shedding of the endothelial glycocalyx following ischaemia/reperfusion.}, author={D. Chappell and Matthias Jacob and Klaus F Hofmann-Kiefer and Markus Rehm and Ulrich Welsch and Peter F Conzen and Bernhard Becker}, journal={Cardiovascular research}, year={2009}, volume={83 2}, pages={388-96} }