Antithrombin: structure, genomic organization, function and inherited deficiency.

@article{Lane1989AntithrombinSG,
  title={Antithrombin: structure, genomic organization, function and inherited deficiency.},
  author={David A Lane and Rosario Caso},
  journal={Bailliere's clinical haematology},
  year={1989},
  volume={2 4},
  pages={
          961-98
        }
}
  • David A Lane, Rosario Caso
  • Published in
    Bailliere's clinical…
    1989
  • Biology, Medicine
  • Antithrombin is a major plasma protein inhibitor of proteinases generated during blood coagulation; it plays an important role in the regulation of thrombin in blood. The anticoagulant heparin greatly accelerates the rate of inactivation of proteinases by antithrombin, predominantly through its well defined, highly specific binding reaction with the inhibitor, but also through a less strictly defined interaction with some of the proteinases (such as thrombin). There is evidence for an analogous… CONTINUE READING

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