Antispermatogenic and antifertility effects of fruits of Piper nigrum L. in mice.

@article{Mishra2009AntispermatogenicAA,
  title={Antispermatogenic and antifertility effects of fruits of Piper nigrum L. in mice.},
  author={Raghav Kumar Mishra and Shio Kumar Singh},
  journal={Indian journal of experimental biology},
  year={2009},
  volume={47 9},
  pages={
          706-14
        }
}
Effect of oral administration (25 and 100 mg/kg body wt/day, for 20 and 90 days) of fruit powder of Piper nigrum L. on the male reproductive organs of mice, Parkes strain, was investigated. Various reproductive end points such as organs weight, histopathology, sperm parameters, sialic acid and fructose contents, and fertility indices were assessed. Histologically, testes in treated mice, except in those treated with 100 mg of dose for 90 days, showed non-uniform degenerative changes in the… CONTINUE READING

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