Antispasmodic effects and structure-activity relationships of labdane diterpenoids from Marrubium globosum ssp. libanoticum.

Abstract

Marrubium globosum ssp. libanoticum is a medicinal plant used in Lebanon to reduce pain and smooth muscle spasms. A chloroform extract obtained from M. globosum aerial parts reduced acetylcholine-induced contractions in the isolated mouse ileum. The purification of this extract identified, among 12 isolated labdane diterpenoids, four new compounds, named 13… (More)
DOI: 10.1021/np9002756

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Cite this paper

@article{Rigano2009AntispasmodicEA, title={Antispasmodic effects and structure-activity relationships of labdane diterpenoids from Marrubium globosum ssp. libanoticum.}, author={Daniela Rigano and Gabriella Aviello and Maurizio Bruno and Carmen Formisano and Sergio Rosselli and Raffaele Capasso and Felice Senatore and Angelo A Izzo and Francesca Borrelli}, journal={Journal of natural products}, year={2009}, volume={72 8}, pages={1477-81} }