Antisense transcription in the human cytomegalovirus transcriptome.

  title={Antisense transcription in the human cytomegalovirus transcriptome.},
  author={Guojuan Zhang and Bindu Raghavan and Mark S. Kotur and Jacquelyn Cheatham and Daniel D. Sedmak and Charles R Cook and James W. Waldman and Joanne Trgovcich},
  journal={Journal of virology},
  volume={81 20},
Human cytomegalovirus (HCMV) infections are prevalent in human populations and can cause serious diseases, especially in those with compromised or immature immune systems. The HCMV genome of 230 kb is among the largest of the herpesvirus genomes. Although the entire sequence of the laboratory-adapted AD169 strain of HCMV has been available for 18 years, the precise number of viral genes is still in question. We undertook an analysis of the HCMV transcriptome as an approach to enumerate and… CONTINUE READING