Antisense therapy for restenosis following percutaneous coronary intervention.

@article{Kipshidze2005AntisenseTF,
  title={Antisense therapy for restenosis following percutaneous coronary intervention.},
  author={Nickolas Kipshidze and Mykola Tsapenko and Patrick I Iversen and Denis R. Burger},
  journal={Expert opinion on biological therapy},
  year={2005},
  volume={5 1},
  pages={
          79-89
        }
}
Recent advances in vascular gene transfer have shown potential new treatment modalities for cardiovascular disease, particularly in the treatment of vascular restenosis. The antisense approach to inhibiting gene expression involves introducing oligonucleotides complementary to mRNA into cells in order to block any one of the following processes: uncoiling of DNA, transcription of DNA, export of RNA, DNA splicing, RNA stability, or RNA translation involved in the synthesis of proteins in… CONTINUE READING
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