Antisense RNA gene therapy for studying and modulating biological processes

@article{Weiss1999AntisenseRG,
  title={Antisense RNA gene therapy for studying and modulating biological processes},
  author={B. Weiss and G. Davidkova and L. Zhou},
  journal={Cellular and Molecular Life Sciences CMLS},
  year={1999},
  volume={55},
  pages={334-358}
}
Abstract. Agents that produce their effects through an antisense mechanism offer the possibility of developing highly specific alternatives to traditional pharmacological antagonists, thereby providing a novel class of therapeutic agents, ones which act at the level of gene expression. Among the antisense compounds, antisense RNA produced intracellularly by an expression vector has been used extensively in the past several years. This review considers the advantages of the antisense RNA… Expand
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