Antiretroviral therapy adherence in Brazil

@article{Nemes2004AntiretroviralTA,
  title={Antiretroviral therapy adherence in Brazil},
  author={M. I. B. Nemes and Her{\'a}clito Barbosa de Carvalho and M F Souza},
  journal={AIDS},
  year={2004},
  volume={18},
  pages={S15-S20}
}
Objectives: This study evaluated the adherence to antiretroviral therapy (ART) in 322 Brazilian outpatient services located in seven states providing care to 87 000 patients (72%) under ART. Methods: A previous study classified the 322 health services into four levels of quality of care. Sixty of them were randomly chosen on the basis of these levels. A cross-section of 1972 patients under ART visiting these services was interviewed using a structured questionnaire. Patients who reported taking… 

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References

SHOWING 1-10 OF 32 REFERENCES

Factors associated with adherence to antiretroviral medication in HIV-infected patients

TLDR
The results suggest that adherence with antiretroviral medication is a multidimensional concept and every effort should be made to assess in individuals those variables found to affect adherence and alter them whenever possible.

Predictors of self-reported adherence and plasma HIV concentrations in patients on multidrug antiretroviral regimens.

TLDR
Nonadherence to combination antiretroviral medications is common and is associated with increased levels of plasma HIV, and programs and clinical efforts to improve medication taking should strive to integrate medications better into patients' daily routines and to improve patients' confidence in their ability to take medications correctly.

Predictors of Self‐Reported Adherence and Plasma HIV Concentrations in Patients on Multidrug Antiretroviral Regimens

TLDR
Nonadherence to combination antiretroviral medications is common and is associated with increased levels of plasma HIV, and programs and clinical efforts to improve medication taking should strive to integrate medications better into patients' daily routines and to improve patients' confidence in their ability to take medications correctly.

Predictors of self-reported adherence in persons living with HIV disease.

TLDR
Findings support the need to treat symptoms, particularly depression, and to understand clients' perceptions of their environment as strategies to enhance adherence, and expand the concept of adherence in HIV care beyond medication adherence to include following instructions and keeping appointments.

Adherence of human immunodeficiency virus-infected patients to antiretroviral therapy.

  • N. SinghS. Berman M. Wagener
  • Medicine, Psychology
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • 1999
TLDR
Satisfaction with social support and coping style significantly impacted adherence and likely accounted for the observed racial difference in adherence among HIV-infected patients.

Dyslipidaemia in HIV-infected patients: association with adherence to potent antiretroviral therapy

TLDR
Dyslipidaemia in patients with HIV infection was significantly associated with adherence to protease inhibitor (PI) therapy and with the markers of clinical response to antiretroviral therapy through a prospective, cross-sectional cohort study.

Avaliação da aderência aos anti-retrovirais em pacientes com infecção pelo HIV/Aids

TLDR
The educational level, age and time of antiretroviral use were the most important predictors of compliance to antireTroviral drugs, and to improve treatment compliance there is a need to have treatment regimens with less side effects.

Adherence, side effects and efficacy of stavudine plus lamivudine plus nelfinavir in treatment-experienced HIV-infected patients.

TLDR
Overall adherence to the employed HAART regimen was poor and female sex and low baseline HIV RNA were associated with better adherence, which was the main reasons to stop therapy.

Detrimental effects of continued illicit drug use on the treatment of HIV-1 infection.

TLDR
Active drug use was strongly associated with underutilization of HAART, nonadherence, and inferior virologic and immunologic responses to therapy, whereas former drug users and non-drug users were similar in all outcomes.

Detrimental Effects of Continued Illicit Drug Use on the Treatment of HIV‐1 Infection

TLDR
Active drug use was strongly associated with underutilization of HAART, nonadherence, and inferior virologic and immunologic responses to therapy, whereas former drug users and non‐drug users were similar in all outcomes.