Antiretroviral prophylaxis for HIV prevention in heterosexual men and women.

@article{Baeten2012AntiretroviralPF,
  title={Antiretroviral prophylaxis for HIV prevention in heterosexual men and women.},
  author={Jared M Baeten and Deborah Donnell and Patrick Ndase and Nelly R. Mugo and James David Campbell and Jonathan Wangisi and Jordan W. Tappero and Elizabeth Anne Bukusi and Craig R Cohen and Elly Tebasooke Katabira and Allan Ross Ronald and Elioda Tumwesigye and Edwin Were and Kenneth H. Fife and James N Kiarie and Carey Farquhar and Grace C John-Stewart and Aloysious Kakia and Josephine Odoyo and Akasiima Mucunguzi and Edith Nakku-Joloba and Rogers Twesigye and Kenneth Kamuri Ngure and Cosmas Apaka and Harrison Tamooh and Fridah Gabona and Gustavo F Doncel and Dana DeVange Panteleeff and Katherine M. Thomas and Lara Kidoguchi and Meighan Krows and Jennifer Revall and Susan A. Morrison and Harald Haugen and Mira Emmanuel-Ogier and Lisa Ondrejcek and Robert W. Coombs and Lisa M. Frenkel and Craig L. Hendrix and Namandj{\'e} N Bumpus and David R. Bangsberg and Jessica E Haberer and Wendy S. Stevens and Jairam R Lingappa and Connie L Celum},
  journal={The New England journal of medicine},
  year={2012},
  volume={367 5},
  pages={
          399-410
        }
}
BACKGROUND Antiretroviral preexposure prophylaxis is a promising approach for preventing human immunodeficiency virus type 1 (HIV-1) infection in heterosexual populations. METHODS We conducted a randomized trial of oral antiretroviral therapy for use as preexposure prophylaxis among HIV-1-serodiscordant heterosexual couples from Kenya and Uganda. The HIV-1-seronegative partner in each couple was randomly assigned to one of three study regimens--once-daily tenofovir (TDF), combination… CONTINUE READING

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