Antiretroviral preexposure prophylaxis for heterosexual HIV transmission in Botswana.

Abstract

BACKGROUND Preexposure prophylaxis with antiretroviral agents has been shown to reduce the transmission of human immunodeficiency virus (HIV) among men who have sex with men; however, the efficacy among heterosexuals is uncertain. METHODS We randomly assigned HIV-seronegative men and women to receive either tenofovir disoproxil fumarate and emtricitabine… (More)
DOI: 10.1056/NEJMoa1110711

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