Antiresorptive agents and osteoclast apoptosis.

@article{Stern2007AntiresorptiveAA,
  title={Antiresorptive agents and osteoclast apoptosis.},
  author={Paula H. Stern},
  journal={Journal of cellular biochemistry},
  year={2007},
  volume={101 5},
  pages={
          1087-96
        }
}
Antiresorptive agents have proven to be effective therapies for the treatment of bone diseases associated with excessive osteoclast activity. Decreased osteoclast formation, inhibition of osteoclast actions, and reduced osteoclast survival represent mechanisms by which antiresorptive agents could act. The goals of this article are to present the evidence that antiresorptive agents can decrease osteoclast survival through apoptosis, to review the mechanisms by which they are thought to activate… CONTINUE READING
BETA

Similar Papers

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 13 CITATIONS

Protocatechuic acid inhibits osteoclast differentiation and stimulates apoptosis in mature osteoclasts.

  • Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
  • 2016
VIEW 1 EXCERPT
CITES BACKGROUND

Tumour macrophages as potential targets of bisphosphonates

  • Journal of Translational Medicine
  • 2011
VIEW 2 EXCERPTS
CITES BACKGROUND