Antipsychotic use and myocardial infarction in older patients with treated dementia.

  title={Antipsychotic use and myocardial infarction in older patients with treated dementia.},
  author={Antoine Pariente and Annie Fourrier-R{\'e}glat and Thierry Ducruet and Paddy Farrington and Sarah-Gabrielle B{\'e}land and Jean-François Dartigues and Nicholas Moore and Yola Moride},
  journal={Archives of internal medicine},
  volume={172 8},
  pages={648-53; discussion 654-5}
BACKGROUND Antipsychotic agents (APs) are commonly prescribed to older patients with dementia. Antipsychotic use is associated with an increased risk of ischemic stroke in this population. Our study aimed to investigate the association of AP use with the risk of acute myocardial infarction (MI). METHODS A retrospective cohort of community-dwelling older patients who initiated cholinesterase inhibitor treatment was identified between January 1, 2000, and December 31, 2009, using the Quebec… CONTINUE READING
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