Antipsychotic effect of electroconvulsive therapy is related to normalization of subgenual cingulate theta activity in psychotic depression.

@article{McCormick2009AntipsychoticEO,
  title={Antipsychotic effect of electroconvulsive therapy is related to normalization of subgenual cingulate theta activity in psychotic depression.},
  author={Laurie M. McCormick and Thoru Yamada and Malcolm Yeh and Michael C. Brumm and R. W. Thatcher},
  journal={Journal of psychiatric research},
  year={2009},
  volume={43 5},
  pages={553-60}
}
OBJECTIVE Electroconvulsive therapy (ECT) is one of the most effective options available for treating depressive and psychotic symptoms in a variety of disorders. While the exact mechanism of ECT is unclear, it is known to increase metabolism and blood flow specifically in the anterior cingulate cortex (ACC). The ACC is a cortical generator of theta rhythms, which are abnormal in patients with depression and psychotic disorders. Since patients with psychotic depression are known to respond… CONTINUE READING
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