Antipsychotic drugs and extrapyramidal side effects in first episode psychosis: a systematic review of head-head comparisons.

@article{Haddad2012AntipsychoticDA,
  title={Antipsychotic drugs and extrapyramidal side effects in first episode psychosis: a systematic review of head-head comparisons.},
  author={Peter M. Haddad and Amlan Das and Sarvenaz Keyhani and Imran Bashir Chaudhry},
  journal={Journal of psychopharmacology},
  year={2012},
  volume={26 5 Suppl},
  pages={
          15-26
        }
}
This systematic review aimed to determine whether the risk of extrapyramidal side effects (EPS) differed between antipsychotic drugs used in first episode psychosis (FEP). We identified 11 RCTs comparing two or more antipsychotics in FEP and reporting on EPS. All trials assessed one or more second generation antipsychotics (SGAs), one assessed chlorpromazine, one zuclopenthixol and seven trials assessed haloperidol. Assessment and reporting of EPS varied. Compared with one or more SGA… CONTINUE READING

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