Antipsychotic-Induced Dopamine Supersensitivity Psychosis: Pharmacology, Criteria, and Therapy.

@article{Chouinard2017AntipsychoticInducedDS,
  title={Antipsychotic-Induced Dopamine Supersensitivity Psychosis: Pharmacology, Criteria, and Therapy.},
  author={Guy Chouinard and Anne-No{\"e}l Samaha and Virginie-Anne Chouinard and Charles-Siegfried Peretti and Nobuhisa Kanahara and Masayuki Takase and Masaomi Iyo},
  journal={Psychotherapy and psychosomatics},
  year={2017},
  volume={86 4},
  pages={
          189-219
        }
}
The first-line treatment for psychotic disorders remains antipsychotic drugs with receptor antagonist properties at D2-like dopamine receptors. However, long-term administration of antipsychotics can upregulate D2 receptors and produce receptor supersensitivity manifested by behavioral supersensitivity to dopamine stimulation in animals, and movement disorders and supersensitivity psychosis (SP) in patients. Antipsychotic-induced SP was first described as the emergence of psychotic symptoms… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 13 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 195 REFERENCES